- 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide, monomethanesulfonate
- CML cABL kits ckit platelet-derived mesilate 152459-95-5 75-75-2 gleevec CGP-57148B glivec STI571 bcrabl R-10(-) 10(–)
Imatinib is an inhibitor of the receptor tyrosine kinases c-Abl, Bcr-Abl, PDGFR, and c-Kit.{47196} It inhibits ligand-stimulated autophosphorylation of PDGFR and c-Kit (IC50s = ~0.3 and ~0.1 μM, respectively).{47196,47197} Imatinib inhibits the proliferation of Bcr-Abl-dependent R10(–) cells (IC50s = ~35-40 nM) and HMC-1 cells expressing constitutively active c-Kit in a concentration-dependent manner.{47196, 20180} It prolongs survival in a mouse model of chronic myeloid leukemia when administered at a dose of 100 mg/kg twice per day.{20177} Formulations containing imatinib have been used in the treatment of various cancers.
Bertin Pharma
在过去的30年里，Bertin生物试剂在开发酶免疫分析试剂盒方面一直在开发一种独特的技术。
Over the past 30 years, Bertin Bioreagent has been developing a unique know-how in the development of enzyme immunoassay kits thanks to its outstanding scientific teams. This expertise is twofold: it enables the development of innovative and high quality products on biomarkers of interest and advises and accompanies our customers in their research.
品牌 | 货号 | 名称 | 规格 |
Bertin Pharma | 10006546 | CAY10465 | 1mg 5mg 10mg 50mg |
Bertin Pharma | 16935 | Cariporide | 5mg 10mg 50mg 100mg |
Bertin Pharma | V01411201 | Polyclonal rabbit anti-turbot Vitellogenin Antibody - CS-2 | 100ul 500ul |
Bertin Pharma | 15868 | Ivabradine (hydrochloride) | 10mg 50mg 100mg 250mg |
Bertin Pharma | 15552 | CCT137690 | 5mg 10mg 50mg |
Bertin Pharma | 16093 | Myrtillin | 500ug 1mg 5mg 10mg |
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