- 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide, hydrate
- inhibitors inhibits inhibitions TGF-β1 TGFβ1 receptors ALK5 ALK4 ALK7 ALKs BMP ALK2 ALK3 ALK6 kinases Smad fibrosis cancers renewal embryonic stems cells induced pluripotent differentiation SB431542 sb431542 sb 431542 301836-41-9 1049727-65-2
SB-431542 is a potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 = 94 nM){16928}. It is a less potent antagonist of ALK4 (IC50 = 140 nM){16992} and ALK7.{16927} It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested.{16927} SB-431542 specifically blocks Smad signaling, reducing gene expression relevant to fibrosis and cancer.{16927} Through its effects on ALK/Smad signaling, SB-431542 suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation.{17335,17336}
Bertin Pharma
在过去的30年里，Bertin生物试剂在开发酶免疫分析试剂盒方面一直在开发一种独特的技术。
Over the past 30 years, Bertin Bioreagent has been developing a unique know-how in the development of enzyme immunoassay kits thanks to its outstanding scientific teams. This expertise is twofold: it enables the development of innovative and high quality products on biomarkers of interest and advises and accompanies our customers in their research.
品牌 | 货号 | 名称 | 规格 |
Bertin Pharma | 10006546 | CAY10465 | 1mg 5mg 10mg 50mg |
Bertin Pharma | 16935 | Cariporide | 5mg 10mg 50mg 100mg |
Bertin Pharma | V01411201 | Polyclonal rabbit anti-turbot Vitellogenin Antibody - CS-2 | 100ul 500ul |
Bertin Pharma | 15868 | Ivabradine (hydrochloride) | 10mg 50mg 100mg 250mg |
Bertin Pharma | 15552 | CCT137690 | 5mg 10mg 50mg |
Bertin Pharma | 16093 | Myrtillin | 500ug 1mg 5mg 10mg |
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