- N5-[imino(nitroamino)methyl]-L-ornithine, methyl ester, monohydrochloride
- nitric oxide synthases inhibitors NOS inhibits
L-NAME requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor (L-NNA).{5433} L-NNA exhibits some selectivity for inhibition of neuronal and endothelial isoforms. It exhibits Ki values of 15 nM, 39 nM, and 4.4 µM for nNOS (bovine), eNOS (human), and iNOS (mouse), respectively.{5344,1857,5648} The reported Ki value for the inhibition of iNOS ranges from 4-65 µM.{1857,1901} L-NAME inhibits cGMP formation in endothelial cells with an IC50 of 3.1 µM (in the presence of 30 µM arginine) and reverses the vasodilation effects of acetylcholine in rat aorta rings with an EC50 of 0.54 µM.{1211,1855}
Bertin Pharma
在过去的30年里，Bertin生物试剂在开发酶免疫分析试剂盒方面一直在开发一种独特的技术。
Over the past 30 years, Bertin Bioreagent has been developing a unique know-how in the development of enzyme immunoassay kits thanks to its outstanding scientific teams. This expertise is twofold: it enables the development of innovative and high quality products on biomarkers of interest and advises and accompanies our customers in their research.
品牌 | 货号 | 名称 | 规格 |
Bertin Pharma | 10006546 | CAY10465 | 1mg 5mg 10mg 50mg |
Bertin Pharma | 16935 | Cariporide | 5mg 10mg 50mg 100mg |
Bertin Pharma | V01411201 | Polyclonal rabbit anti-turbot Vitellogenin Antibody - CS-2 | 100ul 500ul |
Bertin Pharma | 15868 | Ivabradine (hydrochloride) | 10mg 50mg 100mg 250mg |
Bertin Pharma | 15552 | CCT137690 | 5mg 10mg 50mg |
Bertin Pharma | 16093 | Myrtillin | 500ug 1mg 5mg 10mg |
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